INFLUENCE OF GENDER ON PAIN, QUALITY OF LIFE, AND PHYSICAL ACTIVITY IN PATIENTS WITH KNEE OSTEOARTHRITIS
DOI:
https://doi.org/10.18006/2021.9(Spl-1-GCSGD_2020).S139.S147Keywords:
Pain, Knee osteoarthritis, Physical activity, Quality of lifeAbstract
Osteoarthritis is the most common cause of knee pain which contributes to adults’ disability. Females have an increased risk of knee osteoarthritis. However, little is known about the gender influence in pain perception, quality of life (QOL), and physical activity. Hence, this study aimed to investigate the influence of gender on pain perception, QOL, and physical activity in patients with knee osteoarthritis. A cross-sectional study design with a total of 186 patients(mean age of 56.64 ± 6.49) with knee osteoarthritis were recruited. Pain intensity, level of physical activity, and QOL of patients were assessed using a visual analog scale (VAS), global physical activity questionnaire (GPAQ), and Short Form-36 (SF-36) questionnaire. Among the studied patients, 52% of patients with knee osteoarthritis had a relatively low level of physical activity with females representing the majority of them. Lower mean was observed in QOL and physical activity whereas pain intensity was higher in females compared to males (p < 0.05). Pearson correlation demonstrated a strong negative correlation between physical activity and pain (r = -0.77, n = 186, p <0.01), and a weak correlation exist between physical activity and all domains of QOL except for the functional capacity and body pain. Majority of female participants with knee osteoarthritis exhibit poor QOL, physical activity, and increased pain intensity as compared to males. Clinicians need to be aware of the influence of gender in treating patients with knee osteoarthritis.
References
Adamson J, Hunt K, Ebrahim S (2003) Socioeconomic position, occupational exposures, and gender: the relation with locomotor disability in early old age. Journal of Epidemiology & Community Health 57(6): 453-455.
Alenazi AM, Alshehri MM, Alothman S, Alqahtani BA, Rucker J, Sharma N, Segal NA, Bindawas SM, Kluding PM (2020) The Association of Diabetes with Knee Pain Severity and Distribution in people with Knee osteoarthritis using Data from the osteoarthritis initiative. Scientific Reports 10(1): 1-8.
Alkan BM, Fidan F, Tosun A, Ardıçoğlu Ö (2014) Quality of life and self-reported disability in patients with knee osteoarthritis. Modern Rheumatology 24(1): 166-171.
Ayis S, Dieppe P (2009) The natural history of disability and its determinants in adults with lower limb musculoskeletal pain. The Journal of Rheumatology 36(3): 583-591.
Bize R, Johnson JA, Plotnikoff RC (2007) Physical activity level and health-related quality of life in the general adult population: a systematic review. Preventive Medicine 45(6): 401-415.
Bull FC, Maslin TS, Armstrong T (2009) Global physical activity questionnaire (GPAQ): nine country reliability and validity study. Journal of Physical Activity and Health 6(6): 790-804.
Boutron I, Rannou F, Jardinaud-Lopez M, Meric G, Revel M, Poiraudeau S (2008) Disability and quality of life of patients with knee or hip osteoarthritis in the primary care setting and factors associated with general practitioners' indication for prosthetic replacement within 1 year. Osteoarthritis and Cartilage 16(9): 1024-1031.
Chen D, Shen J, Zhao W, Wang T, Han L, Hamilton JL, Im HJ (2017) Osteoarthritis: toward a comprehensive understanding of pathological mechanism. Bone Research 5(1): 1- 13.
Chesterton LS, Barlas P, Foster NE, Baxter GD, Wright CC (2003) Gender differences in pressure pain threshold in healthy humans. Pain 101(3): 259-266.
Chinese Orthopaedic Association (2010) Diagnosis and treatment of osteoarthritis. Orthopaedic Surgery 2(1): 1.
Crichton N (2001) Visual analogue scale (VAS). Journal of Clinical Nursing 10(5): 706-6.
Dekker J, van Dijk GM, Veenhof C (2009). Risk factors for functional decline in osteoarthritis of the hip or knee. Current Opinion in Rheumatology 21(5): 520-524.
Dillon CF, Rasch EK, Gu Q, Hirsch R (2006) Prevalence of knee osteoarthritis in the United States: arthritis data from the Third National Health and Nutrition Examination Survey1991-94. The Journal of Rheumatology 33(11): 2271-2279.
Dominick KL, Ahern FM, Gold CH, Heller DA (2004) Health related quality of life and health service use among older adults with osteoarthritis. Arthritis Care & Research 51(3): 326-331.
Dunlop DD, Semanik P, Song J, Manheim LM, Shih V, Chang RW (2005) Risk factors for functional decline in older adults with arthritis. Arthritis & Rheumatism 52(4): 1274-1282.
Dunlop DD, Semanik P, Song J, Sharma L, Nevitt M, Jackson R, Osteoarthritis Initiative Investigators (2010) Moving to maintain function in knee osteoarthritis: evidence from the osteoarthritis initiative. Archives of Physical Medicine and Rehabilitation 91(5): 714-721.
Elliott AL, Kraus VB, Fang F, Renner JB, Schwartz TA, Salazar A, Jordan JM (2007) Joint-specific hand symptoms and self-reported and performance-based functional status in African–Americans and Caucasians: The Johnston County Osteoarthritis Project. Annals of the rheumatic diseases 66(12): 1622-1626.
Elizabeth W, Rena C (2011) The impact of osteoarthritis on psychological wellbeing. British Journal of Nursing 20(4): 243-246.
Eyre DR (2004) Collagens and cartilage matrix homeostasis. Clinical Orthopaedics and Related Research 427: S118-S122.
Ferre IM, Roof MA, Anoushiravani AA, Wasterlain AS, Lajam CM (2019) Understanding the observed sex discrepancy in the prevalence of osteoarthritis. The Journal of Bone and Joint Surgery 7(9): e8.
Hame SL, Alexander RA (2013) Knee osteoarthritis in women. Current Reviews in Musculoskeletal Medicine 6(2): 182-187.
Hamrik Z, Sigmundová D, Kalman M, Pavelka J, Sigmund E (2014) Physical activity and sedentary behaviour in Czech adults: results from the GPAQ study. European journal of sport science 14(2): 193-198.
Hanna FS, Teichtahl AJ, Wluka AE, Wang Y, Urquhart DM, English DR, Giles GG, Cicuttini FM (2009) Women have increased rates of cartilage loss and progression of cartilage defects at the knee than men: a gender study of adults without clinical knee osteoarthritis. Menopause 16(4): 666-670.
Herrmann SD, Heumann KJ, Der Ananian CA, Ainsworth BE (2013) Validity and reliability of the global physical activity questionnaire (GPAQ). Measurement in Physical Education and Exercise Science 17(3): 221-235.
Heyland DK, Hopman W, Coo H, Tranmer J, McColl MA (2000) Long-term health-related quality of life in survivors of sepsis. Short Form 36: a valid and reliable measure of health-related quality of life. Critical care medicine 28(11): 3599-3605.
Kahl C, Cleland JA (2005) Visual analogue scale, numeric pain rating scale and the McGill Pain Questionnaire: an overview of psychometric properties. Physical Therapy Reviews 10(2): 123-128.
Keefe FJ, Lefebvre JC, Egert JR, Affleck G, Sullivan MJ, Caldwell DS (2000) The relationship of gender to pain, pain behavior and disability in osteoarthritis patients: the role of catastrophizing. Pain 87(3): 325-334.
Klavestrand J, Vingård E (2009) Retracted: The relationship between physical activity and health related quality of life: A systematic review of current evidence. Scandinavian Journal of Medicine & Science in Sports 19(3): 300-312.
Lam CL, Lauder IJ (2000) The impact of chronic diseases on the health-related quality of life (HRQOL) of Chinese patients in primary care. Family Practice 17(2): 159-166.
Loza E, Lopez Gomez JM, Abasolo L, Maese J, Carmona L, Batlle Gualda E, Artrocad Study Group (2009) Economic burden of knee and hip osteoarthritis in Spain. Arthritis Care & Research 61(2): 158-165.
McPhee JS, French DP, Jackson D, Nazroo J, Pendleton N, Degens H (2016) Physical activity in older age: perspectives for healthy ageing and frailty. Biogerontology 17(3): 567-580.
Mesci E, Icagasioglu A, Mesci N, Turgut ST (2015). Relation of physical activity level with quality of life, sleep and depression in patients with knee osteoarthritis. Northern clinics of Istanbul 2(3): 215.
Neogi T (2013) The epidemiology and impact of pain in osteoarthritis. Osteoarthritis and Cartilage 21(9): 1145-1153.
Prieto-Alhambra D, Judge A, Javaid MK, Cooper C, Diez-Perez A, Arden NK (2014) Incidence and risk factors for clinically diagnosed knee, hip and hand osteoarthritis: influences of age, gender and osteoarthritis affecting other joints. Annals of the Rheumatic Diseases 73(9): 1659-1664.
Primorac D, Molnar V, Rod E, Jeleč Ž, Čukelj F, Matišić V, Vrdoljak T, Hudetz D, Hajsok H, Borić I (2020) Knee Osteoarthritis: A Review of Pathogenesis and State-Of-The-Art Non-Operative Therapeutic Considerations. Genes 11(8): 854.
Rapp SR, Rejeski WJ, Miller ME (2000). Physical function among older adults with knee pain: the role of pain coping skills. Arthritis Care & Research 13(5): 270-279.
Riley III JL, Robinson ME, Wise EA, Myers CD, Fillingim RB (1998) Sex differences in the perception of noxious experimental stimuli: a meta-analysis. Pain 74(2-3): 181-187.
Rosenberg DE, Bombardier CH, Hoffman JM, Belza B (2011) Physical activity among persons aging with mobility disabilities: shaping a research agenda. Journal of Aging Research, 2011:708510.
Salaffi F, Carotti M, Stancati A, Grassi W (2005) Health-related quality of life in older adults with symptomatic hip and knee osteoarthritis: a comparison with matched healthy controls. Aging Clinical and Experimental Research 17(4): 255-263.
Sharma A, Kudesia P, Shi Q, Gandhi R (2016) Anxiety and depression in patients with osteoarthritis: impact and management challenges. Open access Rheumatology: Research and Reviews 8: 103 - 113.
Somers TJ, Keefe FJ, Pells JJ, Dixon KE, Waters SJ, Riordan PA, Blumenthal JA, McKee DC, LaCaille L, Tucker JM, Schmitt D (2009) Pain catastrophizing and pain-related fear in osteoarthritis patients: relationships to pain and disability. Journal of Pain and Symptom Management 37(5): 863-872.
Sowers M, Lachance L, Hochberg M, Jamadar D (2000) Radiographically defined osteoarthritis of the hand and knee in young and middle-aged African American and Caucasian women. Osteoarthritis and Cartilage 8(2): 69-77.
Sparling PB, Howard BJ, Dunstan DW, Owen N (2015) Recommendations for physical activity in older adults. British Medical Journal 350: h100
Srikanth VK, Fryer JL, Zhai G, Winzenberg TM, Hosmer D, Jones G (2005) A meta-analysis of sex differences prevalence, incidence and severity of osteoarthritis. Osteoarthritis and Cartilage 13(9): 769-781.
Steultjens MPM, Dekker J, Bijlsma JWJ (2002) Avoidance of activity and disability in patients with osteoarthritis of the knee: the mediating role of muscle strength. Arthritis &Rheumatism: Official Journal of the American College of Rheumatology 46(7): 1784-1788.
Tonelli SM, Rakel BA, Cooper NA, Angstom WL, Sluka KA (2011) Women with knee osteoarthritis have more pain and poorer function than men, but similar physical activity prior to total knee replacement. Biology of Sex Differences 2(1): 12.
Troiano RP, Berrigan D, Dodd KW, Masse LC, Tilert T, McDowell M (2008) Physical activity in the United States measured by accelerometer. Medicine and science in sports and exercise 40(1): 181.
Ware Jr, John E (2000) SF-36 health survey update. Spine 25(24): 3130-3139.
Wilkie R, Peat G, Thomas E, Croft P (2007) Factors associated with restricted mobility outside the home in community dwelling adults ages fifty years and older with knee pain: an example of use of the international classification of functioning to investigate participation restriction. Arthritis Care & Research 57(8): 1381-1389.
Yildiz N, Topuz O, Gungen GO, Deniz S, Alkan H, Ardic F (2010) Health-related quality of life (Nottingham Health Profile) in knee osteoarthritis: correlation with clinical variables and self-reported disability. Rheumatology International 30(12): 1595-1600.
Zakaria ZF, Bakar AA, Hasmoni HM, Rani FA, Kadir SA (2009). Health-related quality of life in patients with knee osteoarthritis attending two primary care clinics in Malaysia: a cross-sectional study. Asia Pacific Family Medicine 8(1): 1-7.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.