ANTIVIRAL PROPERTIES OF MICROALGAE AND CYANOBACTERIA

Manishaa Sri  Mahendran; Sinouvassane  Djearamane; Ling Shing  Wong; Govindaraju  Kasivelu; Anto Cordelia Tanislaus Antony  Dhanapal

doi:10.18006/2021.9(Spl-1-GCSGD_2020).S43.S48

Authors

Manishaa Sri Mahendran Department of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar, 31900 Malaysia
Sinouvassane Djearamane Department of Biomedical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar, 31900 Malaysia
Ling Shing Wong Life Science Division, Faculty of Health and Life Sciences, INTI International University, Nilai, 71800 Malaysia
Govindaraju Kasivelu Centre for Ocean Research, MoES - Earth Science & Technology Cell (Marine Biotechnological Studies), Sathyabama Institute of Science and Technology (Deemed to be University), Chennai, 600119 India.
Anto Cordelia Tanislaus Antony Dhanapal Department of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar, 31900 Malaysia

DOI:

https://doi.org/10.18006/2021.9(Spl-1-GCSGD_2020).S43.S48

Keywords:

Microalgae, Cyanobacteria, Antiviral properties, Bioactive compounds

Abstract

The recent outbreak of Corona Virus Disease (COVID-19) and the surge in accelerating the development of a vaccine to fight against the SARS-CoV-2 virus has imposed greater challenges to humanity worldwide. There is lack of research into the production of effective vaccines and methods of treatment against viral infections. As of now, strategies encompassing antiviral drugs and corticosteroids alongside mechanical respiratory treatment are in practice as frontline treatments. Though studies have reported that microalgae possess antiviral properties, only a few cases have presented the existence of antiviral compounds such as algal polysaccharides, lectins, aggluttinins, scytovirin, algal lipids such as sulfoquinovosyldiacylglycerol (SQDG), monogalactosyldiacylglycerides (MGDG) and digalactosyldiacylglycerides (DGDG), and algal biopigments especially chlorophyll analogues, marennine, phycobiliproteins, phycocyanin, phycoerythrin and allophycocyanin that are derived from marine and freshwater microalgae. Given the chemodiversity of bioactive compounds from microalgae and the present scenario, algal biotechnology is seen as a prospective source of antiviral and anti-inflammatory compounds that can be used to develop antiviral agents. Microalgae with potential as antivirals and microalgae derived functional compounds to treat viral diseases are summarized and can be used as a reference in developing algae-derived antivirals to treat SARS-CoV-2 and other similar viruses.

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