PHYTOCHEMICAL SCREENING OF DIFFERENT ROOT EXTRACTS OF  Ageratum conyzoides AND THEIR POTENTIAL BIOACTIVE PROPERTIES

Tanveer  Ahmad; Tahir  Rasheed; Sarmad Ahmad  Qamar; Muhammad  Bilal

doi:10.18006/2021.9(5).639.646

Authors

Tanveer Ahmad School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
Tahir Rasheed Interdisciplinary Research Center for Advanced Materials, King Fahd University of Petroleum and Minerals (KFUPM), Dhahran 31261, Saudi Arabia.
Sarmad Ahmad Qamar State Key Laboratory of Bioreactor Engineering and School of Biotechnology, East China University of Science and Technology, Shanghai, 200237, China.
Muhammad Bilal School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian, 223003, China.

DOI:

https://doi.org/10.18006/2021.9(5).639.646

Keywords:

Phytochemical screening, Antimicrobial activity, Antioxidant activity, Traditional medicines, Medicinal plants

Abstract

The present study was conducted to determine different classes of secondary metabolites of Ageratum conyzoides root extracts and to evaluate their antioxidant, antibacterial, and antifungal potentialities using various pathogenic fungal and different gram-positive/gram-negative bacterial strains. The roots powder was subjected to ultrasonic-assisted extraction with n-hexane, acetone, ethanol, and EtOH:H₂O(1:1). The screening of phytochemicals indicated the existence of terpenoids, alkaloids, coumarins, sterols, flavonoids, and glycosides in the root extract of A. conyzoides. However, the absence of saponins, tannins, anthocyanidins, anthraquinones, and phlobatannins was observed. The results indicated a reasonable antibacterial (against gram-negative and gram-positive bacteria), and antifungal potential. The antibacterial activity of the ethanolic extract was highest against all four strains of bacteria and was also comparable to the standard medicines used. However, antifungal activity was highest in EtOH:H₂O (1:1) extract. Moderate antioxidant properties were also demonstrated, favoring the importance of the roots of this plant from a medicinal point of view.

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