Cinnamon as a Potential Feed Additive: Beneficial Effects on Poultry Health and Production Performances – An Update
DOI:
https://doi.org/10.18006/2023.11(3).444.461Keywords:
Cinnamon, Natural feed additive, Antibiotic alternative, Essential oil, Poultry health, Gut microbiotaAbstract
According to the Food and Agricultural Organization, global poultry output increased from approximately 115 million tons in 2016 to around 136 million tons in 2023. Poultry production has increased significantly with the dramatic uptick in meat and egg demand. Feed accounts for between 65 and 70 percent of total production costs, making it the largest chicken industry expense. This is why it's important to maximize the transformation of poultry feed into feed with a high biological value while taking as many steps as possible to protect feed quality and reduce feed costs. The use of feed additives in poultry feed has recently gained popularity and has been essential to increase feed efficiency and growth rate, which typically leads to reduced costs. The meat's texture, consistency, and nutritional content are all improved, and its shelf life is lengthened as a bonus. Feed additives are a fantastic tool for boosting a poultry farm's bottom line. For example, cinnamon (Cinnamomum verum) is often used as a traditional feed supplement. Rather than antibiotics, the poultry industry could benefit from using cinnamon as a natural antibiotic replacement, which would benefit animal welfare, consumer health, and the bottom line. The performance index, feed intake, FCE performance, and weight growth of poultry can all be improved by including cinnamon in the feed at varied concentrations. The digestive health and intestinal microbial population of hens are enhanced by a diet containing bioactive components of cinnamon. Cinnamon essential oils' popularity stems from their many valuable features, such as their ability to increase gastric enzyme synthesis and other biofunctional benefits. This review focuses on the possible advantages of cinnamon as a natural feed supplement for chickens, particularly about their intestinal microbiota, blood chemistry, nutrient absorption, gene expression, and immunology.
References
Abd El-Hack, E.M., Alagawany, M., Abdel-Moneim, A.E., Mohammed, N.G., Khafaga, A.F., Bin-Jumah, M., Othman, S.I., Allam, A.A., & Elnesr, S.S. (2020). Cinnamon (Cinnamomum zeylanicum) oil as a potential alternative to antibiotics in poultry. Journal of Antibiotics, 9(5), 210. https://doi.org/10.3390/ antibiotics9050210
Abd El-Hack, M.E., & Alagawany M. (2022). Antibiotic alternatives in poultry and fish feed. Bentham Science Publishers. https://doi.org/10.2174/97898150490151220101
Abdelli, N., Solà-Oriol, D., & Pérez, J.F. (2021). Phytogenic feed additives in poultry: achievements, prospective and challenges. Animals, 11(12), 3471. https://doi.org/10.3390/ani11123471
Abo Ghanima, M.M., Elasdek, M.F., Taha, A.E., Abd El-Hack, M.E., Alagawany, M., Ahmed, B.M., Elshafie, M.M., Mahmoud, M., & El-Sabrout, K. (2020). Effect of housing system and rosemary and cinnamon essential oils on layers performance, egg quality, haematological traits, blood chemistry, immunity, and antioxidant. Journal of Animals, 10(2), 245. https://doi.org/10.3390/ani10020245
Alagawany, M., El-Hindawy, M.M., Mohamed, L.A., Bilal, R.M., & Soomro, J. (2020). The use of cold pressed oils as eco-friendly alternatives for antibiotics in high and low-CP diets of laying Japanese quail. Animal Biotechnology. https://doi.org/10.1080/ 10495398.2020.1837846
Alagawany, M., Farag, M.R., El-Kholy, M.S., El-Sayed, S.A.A., & Dhama, K. (2016). Effect of resveratrol, cinnamaldehyde and their combinations on the antioxidant defense system and ATP release of rabbit erythrocytes: in vitro study. Asian Journal of Animal Science and Veterinary Advances, 12(1), 1-9.
Ali, A., Ponnampalam, E.N., Pushpakunara, G., Cottrell, J.J., Suleria, H.A.R., & Dunshea, F.R. (2021). Cinnamon: A natural feed additive for poultry health and production. Journal of Animals, 11(7): 2026. https://doi: 10.3390/ani11072026
Al-Kassie, G.A. (2009), Influence of two plant extracts derived from thyme and cinnamon on broiler performance. Pakistan Veterinary Journal, 29(4), 169-173.
Alves-Santos, A.M., Araújo Sugizaki, C.S., Lima, G.C., & Naves, M.M.V. (2020). Prebiotic effect of dietary polyphenols: A systematic review. Journal of Functional Foods, 74, 104169. https://doi.org/10.1016/j.jff.2020.104169.
Arain, M.A., Muhammad, S., Faiz Ul, H., Imran, R.R., Zohaib, A.B., Mahmoud, A., & Akhtar, H.S. (2018). Phytochemistry and beneficial impacts of cinnamon (Cinnamomum zeylanicum) as a dietary supplement in poultry diets. World's Poultry Science Journal, 74 (2): 331-346.
Baskara, A. P., Sharma, S., Sener-Aydemir, A., Koger, S., Ariyadi, B., Dono, N. D., Zuprizal, Z., & Metzler-Zebeli, B. U. (2021). Cinnamon bark oil and coconut oil emulsions modified small intestinal motility and barrier function in laying hens in an ex vivo experiment. British Poultry Science, 62(3), 435–442. https://doi.org/10.1080/00071668.2020.1870662.
Bedford, M. (2000). Removal of antibiotic growth promoters from poultry diets: Implications and strategies to minimize subsequent problems. Worlds Poultry Science Journal, 56, 347-365. https://doi.org/10.2141/jpsa.43.378.
Bento, M.H.L., Ouwehand, A.C., Tiihonen, K., Lahtinen, S., Nurminen, P., Saarinen, M.T., Schulze, H., Mygind, T., & Fischer, J. (2013). Essential oils and their use in animal feeds for monogastric animals–Effects on feed quality, gut microbiota, growth performance and food safety: A review. Veterinarni Medicina, 58, 449–458.
Bogusławska-Tryk, M., Szymeczko, R., Piotrowska, A., Burlikowska, K., & Sli´zewska, K. (2015). Ileal and cecal microbial population and ˙short-chain fatty acid profile in broiler chickens fed diets supplemented with lignocellulose. Pakistan Veterinary Journal, 35, 212–216.
Buttar, H.S., Kumar, H., Chandran, D., Tuli, HS, & Dhama, K. (2022), Potential health benefits of using aloe vera as a feed additive in livestock: A mini-review. Indian Veterinary Journal, 99 (01), 09-18.
Chandran, D. (2021), Veterinary phytomedicine in India: A review. International Journal of Scientific Research in Science and Technology, 8(3): 598-605. https://doi.org/10.32628/IJSRST2183135
Chandran, D., Emran, T.B., Nainu, F., Sharun, K., Kumar, M., Mitra, S., Chakraborty, S., Mohapatra, R.K., Tuli, HS, & Dhama, K. (2022). Beneficial effects of dietary Allium sativum (garlic) supplementation on health and production of poultry: A mini-review. Indian Veterinary Journal, 9: 821-824. https://doi. org/10.1002/ptr.7363
Chang, S.T., Chang, L.W., Chang, W.C., & Cheng, S.S. (2008). Antibacterial activities of plant essential oils against Legionella pneumophila. Water Research, 42(1-2), 278-286. https://doi.org/10.1016/j.watres.2007.07.00
Chang, S.T., Chen, P.F., & Chang, S.C. (2001). Antibacterial activity of leaf essential oils and their constituents from Cinnamomum osmophloeum. Journal of Ethnopharmacology, 77, 123-127. https://doi.org/10.1016/S0378-8741(01)00273-2
Chowdhury, S., Mandal, G.P., & Patra, A.K. (2018). Different essential oils in diets of chickens: 1. Growth performance, nutrient utilization, nitrogen excretion, carcass traits and chemical composition of meat. Animal Feed Science and Technology, 236, 86–97. https://doi.org/10.1016/j.anifeedsci.2017.12.002
Chowlu, H., Vidyarthi, V.K., Zuyie, R., & Maiti, CS (2019). Effect of dietary supplementation of cinnamon on the performance of broiler chicken. International Journal of Livestock, 7(2), 83-87.
Ciftci, M., Dalkilic, B., Cerci, I.H., Guler, T., Ertas, O.N., & Arslan, O. (2009). Influence of dietary cinnamon oil supplementation on performance and carcass characteristics in broilers. Journal of Applied Animal Research, 36, 125-128. https://doi.org/10.1080/09712119.2009.9707045
Ciftci, M., Simsek, U.G., Yuce, A., Yilmaz, O., & Dalkilic, B. (2010). Effects of dietary antibiotic and cinnamon oil supplementation on antioxidant enzyme activities, cholesterol levels and fatty acid compositions of serum and meat in broiler chickens. Acta Veterinarica, 79, 33–40. https://doi.org/10.2754/ avb201079010033.
Dawson, J., Miltz, W., Mir, A.K., & Wiessner, C. (2003). Targeting monocyte chemoattractant protein 1 signalling in disease. Expert Opinion Therapeutic Targets, 7, 35–48. https://doi.org/10.1517/14728222.7.1.35
Devi, P.C., Samanta, A.K., Das, B., Kalita, G., Ehera, P.S., & Barman, S. (2018). Effect of plant extracts and essential oil blend as alternatives to antibiotic growth promoters on growth performance, nutrient utilization and carcass characteristics of broiler chicken. Indian Journal of Animal Nutrition, 35, 421–427. http://dx.doi.org/10.5958/2231-6744.2018.00064.6
Dhama, K, Saminathan, M., Jacob, S.S., Singh, M., Karthik, K., Amarpal, Tiwari, R., Sunkara, L.T. Malik, Y.S. & Singh, R.K. (2015b). Effect of immunomodulation and immunomodulatory agents on health with some bioactive principles, modes of action and potent biomedical applications. International Journal of Pharmacology, 11(4): 253-290. DOI: 10.3923/ijp.2015.253.290
Dhama, K., Karthik, K., Khandia, R., Munjal, A., Tiwari, R., Rana, R., Khurana, S.K., Sana, U., Khan, R.U., Alagawany, M., Farag, M.R., Dadar, M., & Joshi, S.K. (2018) Medicinal and therapeutic potential of herbs and plant metabolites / extracts countering viral pathogens - Current knowledge and future prospects. Current Drug Metabolism, 19(3), 236-263. doi: 10.2174/ 1389200219666180129145252.
Dhama, K., Latheef, S.K. Saminathan, M., Samad, H.A., Karthik K, Tiwari, R., Khan, R.U., Alagawany, M., Farag, M.R., Gazi, M.A., Laudadio, V., & Tufarelli, V. (2015a) Multiple beneficial applications and modes of action of herbs in poultry health and production – A review. International Journal of Pharmacology, 11(3), 152-176. DOI: 10.3923/ijp.2015.152.176
Dhama, K., Tiwari, R, Chakraborty, S., Saminathan, M., Kumar, A., Karthik, K., Wani, M.Y., Amarpal, S.S.V., & Rahal, A. (2014). Evidence based antibacterial potentials of medicinal plants and herbs countering bacterial pathogens especially in the era of emerging drug resistance: An integrated update. International Journal of Pharmacology, 10(1), 1-43. https://doi.org/10.3923/ ijp.2014.1.43
Diaz, C., Juan, M., Casanova, N.A., & Miyakawa, M.E.F. (2019). Microbiota, gut health and chicken productivity: What is the connection? Microorganisms, 7, 374. https://doi.org/10.3390/ microorganisms7100374
El-Sabrout, K., Khalifah, A., & Mishra, B. (2023). Application of botanical products as nutraceutical feed additives for improving poultry health and production. Veterinary world, 16(2), 369–379. https://doi.org/10.14202/vetworld.2023.369-379
Erfan, A.M., & Marouf, S. (2019). Cinnamon oil downregulates virulence genes of poultry respiratory bacterial agents and revealed significant bacterial inhibition: An in vitro perspective. Veterinary World, 12(11), 1707-1715. https://doi.org/10.14202/ vetworld.2019.1707-1715
Faghani, M., Rahimian, Y., Rafiee, A., & Namjoo, A.R. (2014). Effect of garlic and cinnamon in comparison to virginiamycin on performance and some haematological parameters in broiler chicks. Research Opinion in Animal & Veterinary Science, 4, 504–507.
Farag, M.R., Alagawany, M., & Tufarelli, V. (2016). In vitro antioxidant activities of resveratrol, cinnamaldehyde and their synergistic effect against cyadox-induced cytotoxicity in rabbit erythrocytes. Drug and Chemical Toxicology, 40(2), 196-205.
Farag, M.R., Mahmoud, A., Abd El-Hack, M.E., Shaaban, S.E., Gihan, G.M., Kuldeep, D., & Nabela, I.E. (2021). Antibiotics as Growth Promoters in Poultry Feeding. In: M. Alagawany, & M.E. Abd El-Hack (eds). Natural Feed Additives Used in the Poultry Industry. Bentham Science Publishers Pte. Ltd. Singapore. https://doi.org/10.2174/97898114884501200101
Garcia, V., Catala-Gregori, P., Hernandez, F., Megias, M., & Madrid, J. (2007). Effect of formic acid and plant extracts on growth, nutrient digestibility, intestine mucosa morphology, and meat yield of broilers. Journal of Applied Poultry Research, 16, 555–562. https://doi.org/10.3382/japr.2006-00116
Gopi, M., Kathirvelan, C., Premchander, D., Vasanthakumar, P., Pangayarselvi, B., Sasikumar, P., & Chandrasekaran, D. (2012). Effect of cinnamon powder (cinnamomum zeylanicum) supplementation on growth performance of broilers. Commercial and rural poultry production: Novel concepts and strategies to meet growing demand and changing consumer needs. Proceedings of the 24th Annual Conference and National Symposium of Indian Poultry Science Association, pp. 35-36.
Habib, M.A., Abozid, M.M., El Sofany, S.A., & Faragalla, S.F. (2021). Antimicrobial potentials of cinnamon and garlic extracts against some foodborne pathogens. Zagazig Journal of Agricultural Research, 48(3), 805-815. https://dx.doi.org/ 10.21608/zjar.2021.191318
Habiba, M.M., Hussein, E.E., Ashry, A.M., El-Zayat, A.M., Hassan, A.M., El-Shehawi, A.M., Sewilam, H., Doan, H.V., & Dawood, M.A.O. (2021). Dietary cinnamon successfully enhanced the growth performance, growth hormone, antibacterial capacity, and immunity of European sea bass (Dicentrarchus labrax). Journal of Animals, 11(7), 2128. https://doi.org/10.3390/ ani11072128
Hartady, T., Syamsunarno, MRAA, Priosoeryanto, B.P., Jasni, S., & Balia, R.L. (2021) Review of herbal medicine works in the avian species. Veterinary World, 14(11), 2889-2906. https://doi.org/ 10.14202%2Fvetworld.2021.2889-2906
Hashemi, S.R., & Davoodi, H. (2010). Phytogenic as new class of feed additive in poultry industry. Journal of Animal & Veterinary Advances, 9, 2295-2304.
Hernandez, F., Madrid, J., Garcia, V., Orengo, J., & Megias, M.D. (2004). Influence of two plant extracts on broilers performance, digestibility, and digestive organ size. Poultry Science, 83, 169–174. https://doi.org/10.1093/ps/83.2.169
Hossain, M., Howlader, A., Islam, M., & Beg, M. (2014). Evaluation of locally available herbs and spices on physical, biochemical and economical parameters on broiler production. International Journal of Plant, Animal and Environmental Sciences, 4, 317–323.
Iqbal, Y., Cottrell, J.J., Suleria, H.A.R., & Dunshea, F.R. (2020). Gut microbiota polyphenol interactions in chicken: A review. Journal of Animals, 10, 1391. https://doi.org/10.3390/ani10081391
Isabel, B., & Santos, Y. (2009). Effects of dietary organic acids and essential oils on growth performance and carcass characteristics of broiler chickens. Journal of Applied Poultry Research, 18, 472-476. https://doi.org/10.3382/japr.2008-00096
Izadnia, H.R., Tahmoorespur, M., Bakhtiarizadeh, M.R., Nassiri, M., & Esmaeilkhanien, S. (2019). Gene expression profile analysis of residual feed intake for Isfahan native chickens using RNA-SEQ data. Italian Journal of Animal Science, 18, 246–260. https://doi.org/10.1080/1828051X.2018.1507625
Jakhetia, V., Patel, R., Khatri, P., Pahuja, N., Garg, S., Pandey, A., & Sharma, S. (2010). Cinnamon: A pharmacological review. Journal of Advanced Scientific Research, 1, 19-23.
Jamroz, D., Wertelecki, T., Houszka, M., & Kamel, C. (2006). Influence of diet type on the inclusion of plant origin active substances on morphological and histochemical characteristics of the stomach and jejunum walls in chicken. Journal of Animal Physiology & Animal Nutrition, 90, 255–268. https://doi.org/ 10.1111/j.1439-0396.2005.00603.x
Jamroz, D., Wiliczkiewicz, A., Wertelecki, T., Orda, J., & Skorupi´nska, J. (2005). Use of active substances of plant origin in chicken diets based on maize and locally grown cereals. British Poultry Science, 46, 485–493. https://doi.org/10.1080/ 00071660500191056
Jayaprakasha, G. K., Rao, L. J., & Sakariah, K. K. (2002). Chemical composition of volatile oil from Cinnamomum zeylanicum buds. Zeitschrift fur Naturforschung. C, Journal of biosciences, 57(11-12), 990–993. https://doi.org/10.1515/znc-2002-11-1206.
Kamel, C. (2001). Tracing modes of action and roles of plant extracts in non-ruminants. Recent Advances in Animal Nutrition, 135-150.
Kanani, P.B., Daneshyar, M., & Najafi, R. (2016). Effects of cinnamon (Cinnamomum zeylanicum) and turmeric (Curcuma longa) powders on performance, enzyme activity, and blood parameters of broiler chickens under heat stress. Poultry Science Journal, 4, 47–53.
Kettunen, H., Ouwehand, A., Schulze, H., & Rautonen, N. (2006). Dietary essential oil supplementation enhanced intestinal immunocompetence in young broiler chick. Reproduction, Nutrition & Development, 46, S101.
Khan, K., Ahmad, N., Tahir, M., & Chand, N. (2022). Alleviation of negative effect of heat stress through supplementations of cinnamon (Cinnamomum zeylanicum) and turmeric (Curcuma longa L) powders in diets of broiler chickens. Animal Biotechnology, 1–9. Advance online publication. https://doi.org/10.1080/10495398.2022.2156351
Kim, Y.S., Lee, Y.M., Kim, H., Kim, J., Jang, D.S., Kim, J.H., & Kim, J.S. (2010). Anti-obesity effect of Morus bombycis root extract: anti-lipase activity and lipolytic effect. Journal of Ethnopharmacology, 130(3), 621-624. https://doi.org/10.3109/ 09637486.2013.832172
Koochaksaraie, R.R., Irani, M., & Gharavysi, S. (2011). The effects of cinnamon powder feeding on some blood metabolites in broiler chicks. Brazilian Journal of Poultry Science, 13, 197-201. https://doi.org/10.1590/S1516-635X2011000300006
Krauze, M., Jurczak, P., Cendrowska-Pinkosz, M., Stępniowska, A., Matusevičius, P., & Ognik, K. (2023). Feasibility of including a phytobiotic containing cinnamon oil in the diet to reduce the occurrence of neurodegenerative changes in broiler chicken tissues. Journal of Animal Feed Science, 32(2), 164–173.
Krauze, M., Cendrowska-Pinkosz, M., Matuseviĉius, P., Stępniowska, A., Jurczak, P., & Ognik, K. (2021). The Effect of Administration of a Phytobiotic Containing Cinnamon Oil and Citric Acid on the Metabolism, Immunity, and Growth Performance of Broiler Chickens. Animals, 11(2), 399. https://doi.org/10.3390/ani11020399
Kumar, M., Tomar, M., Punia, S., Dhakane-Lad, J., Dhumal, S., Changan, S., Senapathy, M., Berwal, M.K., Sampathrajan, V., Sayed, A.A., & Chandran, D. (2022). Plant-based proteins and their multifaceted industrial applications. Lebensmittel-Wissenschaft &Technologie, 154, 112620. https://doi.org/10.1016/ j.lwt.2021.112620
Kumari, N., Kumar, M., Mekhemar, M., Lorenzo, J.M., Pundir, A., Devi, K.B., Prakash, S., Puri, S., Thakur, M., Rathour, S., & Rais, N. (2022). Therapeutic uses of wild plant species used by rural inhabitants of Kangra in the western Himalayan region. South African Journal of Botany, 148, 415-436. https://doi.org/10.3390/ horticulturae7100343
Kuralkar, P., & Kuralkar, S. V. (2021). Role of herbal products in animal production – An updated review. Journal of Ethnopharmacology, 278. https://doi.org/10.1016/j.jep.2021.114246.
Lee, K.W., Everts, H., Kappert, H., Frehner, M., Losa, R., & Beynen, A. (2003). Effects of dietary essential oil components on growth performance, digestive enzymes and lipid metabolism in female broiler chickens. British Poultry Science, 44, 450–457. https://doi.org/10.1080/0007166031000085508
Lee, S.A., Apajalahti, J., Vienola, K., González-Ortiz, G., Fontes, C.M.G.A., & Bedford, M.R. (2017). Age and dietary xylanase supplementation affect ileal sugar residues and short chain fatty acid concentration in the ileum and caecum of broiler chickens. Animal Feed Science & Technology, 234, 29–42. https://doi.org/10.1016/j.anifeedsci.2017.07.017
Lillehoj, H.S., Kim, D.K., Bravo, D.M., & Lee, S.H. (2011). Effects of dietary plant-derived phytonutrients on the genome-wide profiles and coccidiosis resistance in the broiler chickens. BMC Proceedings, 5(4), 1–8.
Lin, C.C., Wu, S.J., Chang, C.H., & Ng, L.T. (2003). Antioxidant activity of Cinnamomum cassia. Phytotherapy Research, 17, 726–730. https://doi.org/10.1002/ptr.1190
Mandal, S., Van Treuren, W., White, R.A., Eggesbø, M., Knight, R., & Peddada, S.D. (2015). Analysis of composition of microbiomes: a novel method for studying microbial composition. Microbial Ecology in Health and Disease, 26(1), 27663. http://dx.doi.org/10.3402/mehd.v26.27663
Marongiu, B., Piras, A., & Porcedda, S. (2007). Supercritical CO2 extract of Cinnamomum zeylanicum: chemical characterization and antityrosinase activity. Journal of Agriculture & Food Chemistry, 55(24), 10022- 10027. https://doi.org/10.1021/jf071938f
Mehdi, Y., Létourneau-Montminy, M.P., Gaucher, M.L., Chorfi, Y., Suresh, G., Rouissi, T., Brar, S.K., Côté. C., Ramirez, A.A., & Godbout, S. (2018). Use of antibiotics in broiler production: Global impacts and alternatives. Animal Nutrition, 4, 170–178. https://doi.org/10.1016/j.aninu.2018.03.002
Mehdipour, Z., & Afsharmanesh, M. (2018). Evaluation of synbiotic and cinnamon (Cinnamomumverum verum) as antibiotic growth promoter substitutions on growth performance, intestinal microbial populations and blood parameters in Japanese quail. Journal of Livestock Science & Technology, 6, 1–8. https://doi.org/10.22103/jlst.2018.10558.1200
Mehdipour, Z., Afsharmanesh, M., & Sami, M. (2013). Effects of dietary synbiotic and cinnamon (Cinnamomum verum) supplementation on growth performance and meat quality in Japanese quail. Livestock Science, 154, 152–157. https://doi.org/10.1016/j.livsci.2013.03.014
Mitra, S., da Silva, L.E., Tuli, HS, & Dhama, K. (2022). Potential health benefits of dietary Curcuma longa (turmeric) supplementation on health and production of poultry: A Mini-review. Indian Veterinary Journal, 99(2), 7-13.
Mountzouris, K., Paraskevas, V., Tsirtsikos, P., Palamidi, I., Steiner, T., Schatzmayr, G., & Fegeros, K. (2011). Assessment of a phytogenic feed additive effect on broiler growth performance, nutrient digestibility and caecal microflora composition. Animal Feed Science Technology, 168, 223–231. https://doi.org/10.1016/j.anifeedsci.2011.03.020
Mueller, K., Blum, N.M., Kluge, H., & Mueller, A.S. (2012). Influence of broccoli extract and various essential oils on performance and expression of xenobiotic-and antioxidant enzymes in broiler chickens. British Journal of Nutrition, 108, 588–602. https://doi.org/10.1017/S0007114511005873
Naderi, M., Akbari, M., Asadi-Khoshoei, E., Khaksar, K., & Khajali, F. (2014). Effects of dietary inclusion of turmeric (Curcuma longa) and cinnamon (Cinnamomum verum) Powders on performance, organs relative weight and some immune system parameters in broiler chickens. Poultry Science Journal, 2, 153–163.
Najafi, S., & Taherpour, K. (2014). Effects of dietary ginger (Zingiber Ofjicinale), cinnamon (Cinnamomum verum), synbiotic and antibiotic supplementation on performance of broilers. Journal of Animal Science Advances, 4, 658–667.
Nawab, A., Ibtisham, F., Li, G., Kieser, B., Wu, J., Liu, W., Zhao, Y., Nawab, Y., Li, K., & Xiao, M. (2018), Heat stress in poultry production: Mitigation strategies to overcome the future challenges facing the global poultry industry. Journal of Thermal Biology, 78, 131–139. https://doi.org/10.1016/j.jtherbio.2018.08.010
Nonaka, I.G., Morimoto, S., & Nishioka, I. (1983). Tannins and related compounds. Part 13. Isolation and structures of trimeric, tetrameric, and pentameric proanthicyanidins from cinnamon. Journal of Chemical Society, 1, 2139-2145. https://doi.org/10.1039/P19830002139
Oakley, B.B., Lillehoj, H.S., Kogut, M.H., Kim, W.K., Maurer, J.J., Pedroso, A., Lee, M.D., Collett, S.R., Johnson, T.J., & Cox, N.A. (2014). The chicken gastrointestinal microbiome. FEMS Microbiology Letters, 360(2), pp.100-112. https://doi.org/10.1111/ 1574-6968.12608
Ouwehand, A.C., Tiihonen, K., Kettunen, H., Peuranen, S., Schulze, H., & Rautonen, N. (2010). In vitro effects of essential oils on potential pathogens and beneficial members of the normal microbiota. Veterinary Medicine, 55, 71–78. https://doi.org/ 10.17221/152/2009-VETMED
Pannee, C., Chandhanee, I., & Wacharee, L. (2014). Antiinflammatory effects of essential oil from the leaves of Cinnamomum cassia and cinnamaldehyde on lipopolysaccharide-stimulated J774A.1 cells. Journal of Advances in Pharmacology & Technology Research, 5, 164–170. https://doi.org/ 10.4103%2F2231-4040.143034
Parham, S., Kharazi, A. Z., Bakhsheshi-Rad, H. R., Nur, H., Ismail, A. F., Sharif, S., RamaKrishna, S., & Berto, F. (2020). Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials. Antioxidants (Basel, Switzerland), 9(12), 1309. https://doi.org/10.3390/antiox9121309
Pathak, M., Mandal, G.P., Patra, A.K., Samanta, I., Pradhan, S., & Haldar, S. (2017). Effects of dietary supplementation of cinnamaldehyde and formic acid on growth performance, intestinal microbiota and immune response in broiler chickens. Animal Production Science, 57, 821–827. https://doi.org/10.1071/AN15816
Platel, K., & Srinivasan, K. (2004). Digestive stimulant action of spices: A myth or reality? Indian Journal of Medical Research, 119, 167-79.
Prakash, G., Savanth V, V., M, P., Chopra, H., Emran, T. B., Dey, A., Dhama, K., & Chandran, D. (2022). Essential oils as valuable feed additive: A narrative review of the state of knowledge about their beneficial health applications and enhancement of production performances in poultry. Journal of Experimental Biology and Agricultural Sciences, 10(6), 1290–1317. https://doi.org/10.18006/ 2022.10(6).1290.1317
Prakash, P., Kumar, M., Kumari, N., Prakash, S., Rathour, S., Thakur, M., Jamwal, R., Janjua, S., Ali, M., Pundir, A., & Puri, S. (2021b). Therapeutic uses of wild plants by rural inhabitants of Maraog region in district Shimla, Himachal Pradesh, India. Horticulturae. 7(10), 343. https://doi.org/10.3390/ horticulturae7100343
Prakash, P., Kumar, M., Pundir, A., Puri, S., Prakash, S., Kumari, N., Thakur, M., Rathour, S., Jamwal, R., Janjua, S., & Ali, M. (2021a). Documentation of commonly used ethnoveterinary medicines from wild plants of the high mountains in Shimla District, Himachal Pradesh, India. Horticulturae, 7(10) 351. https://doi.org/10.3390/horticulturae7100351
Rajan, A., Shabana, A., Krishnan, N., N Anil, K., Krishnan, R., Y, B. S., S Dev, B., J, A., S, M., V R, A., Chakraborty, S., Chopra, H., Dey, A., Sharma, A. K., Dhama, K., & Chandran, D. (2023). Positive impacts of integrating flaxseed meal as a potential feed supplement in livestock and poultry production: Present scientific understanding. Journal of Experimental Biology and Agricultural Sciences, 11(2), 264–279. https://doi.org/10.18006/2023.11(2).264.279
Rajan, N. S., Raida, V K, S., Suresh, S., P S, H., P, S., M, P., R, P., Yatoo, M. I., Chopra, H., Emran, T. B., Dey, A., Dhama, K., & Chandran, D. (2022). Potential effects of essential oils in safeguarding the health and enhancing production performance of livestock animals: The current scientific understanding. Journal of Experimental Biology and Agricultural Sciences, 10(6), 1222–1240. https://doi.org/10.18006/2022.10(6).1222.1240
Rao, P.V., Jayaprakasha, G.K., & Gan, S.H. (2014). Cinnamon: a multifaceted medicinal plant. Evidence-Based Complementary and Alternative Medicine. https://doi.org/10.1155/2014/642942
Rashid, Z., Mirani, ZA, Zehra, S., Gilani, S.M.H., Ashraf, A., Azhar, A., Al-Ghanim, K.A., Al-Misned, F., Al-Mulahim, N., & Mahboob, S. (2020). Enhanced modulation of gut microbial dynamics affecting body weight in birds triggered by natural growth promoters administered in conventional feed. Saudi Journal of Biological Sciences, 27, 2747–2755. https://doi.org/10.1016/j.sjbs.2020.06.027
Redondo, L.M., Chacana, P.A., Dominguez, J.E., & Fernandez, M.M.E. (2014). Perspectives in the use of tannins as alternative to antimicrobial growth promoter factors in poultry. Frontiers in Microbiology, 5, 118. https://doi.org/10.3389/fmicb.2014.00118
Saeed, M., Kamboh, A.A., Syed, S.F., Babazadeh, D., Suheryani, I., Shah, Q.A., Umar, M., Kakar, I., Naveed, M., Abd El-Hack, M.E., & Alagawany, M. (2018). Phytochemistry and beneficial impacts of cinnamon (Cinnamomum zeylanicum) as a dietary supplement in poultry diets. World's Poultry Science Journal, 74(2), 331-346. https://doi.org/10.1017/S0043933918000235
Saeed, S., Rashid, N., Jones, P.G., Ali, M., & Hussain, R. (2010). Synthesis, characterization and biological evaluation of some thiourea derivatives bearing benzothiazole moiety as potential antimicrobial and anticancer agents. European Journal of Medicinal Chemistry, 45(4), 1323-1331. https://doi.org/10.1016/ j.ejmech.2009.12.016
Saied, A.M., Attia, A.I., El-Kholy, M.S., Reda, F.M., & EL Nagar, A.G. (2022). Effect of cinnamon oil supplementation into broiler chicken diets on growth, carcass traits, haemato-biochemical parameters, immune function, antioxidant status and caecal microbial count. Journal of Animal Feed Science, 31(1), 21–33.
Sang-Oh, P., Chae, M.R., Byung-Sung, P., & Jong, H. (2013). The meat quality and growth performance in broiler chickens fed diet with cinnamon powder. Journal of Environmental Biology, 34, 127-133.
Seidavi, A., Tavakoli, M., Asroosh, F., Scanes, C.G., Abd El-Hack, M.E., Naiel, M.A.E., Taha, A.E., Aleya, L., El-Tarabily, K.A., & Swelum, A.A. (2022) Antioxidant and antimicrobial activities of phytonutrients as antibiotic substitutes in poultry feed. Environmental Science and Pollution Research. 29(4), 5006-5031. https://doi.org/10.1007/s11356-021-17401-w
Senanayake, M.U., Lee, H.T., & Wills, R.B.H. (1978). Volatile constituents of cinnamon (Cinnamomum zeylanicum) oils. Journal of Agriculture & Food Chemistry, 26(4), 822-824. https://doi.org/ 10.1021/jf60218a031
Shirzadegan, K. (2014). Reactions of modern broiler chickens to administration of cinnamon powder in the diet. Iranian Journal of Applied Animal Science, 4, 367–371.
Sim sek, Ü.G., Ciftci, M., Do ̆gan, G., & Özçelik, M. (2013). Antioxidant activity of cinnamon bark oil (Cinnamomum zeylanicum L.) in Japanese quails under thermo neutral and heat stressed conditions. Kafkas University Veterinary Journal, 19, 889–894. https://doi.org/10.9775/KVFD.2013.9049
Sim sek, Ü.G., Ciftci, M., Özçelik, M., Azman, M.A., Tonbak, F., & Özhan, N. (2015). Effects of cinnamon and rosemary oils on egg production, egg quality, hatchability traits and blood serum mineral contents in laying quails (Coturnixcoturnix japonica). Ankara University Veterinary Journal, 62, 229–236.
Singh, G., Maurya, S., Cesar, M.P., & Catalan, A.M. (2007). A comparison of chemical, antioxidant and antimicrobial studies of cinnamon leaf and bark volatile oils, oleoresins and their constituents. Food Chemistry Toxicology, 45, 1650-1661. https://doi.org/10.1016/j.fct.2007.02.031
Solanki, D.M., Dave, C.J., Bhanderi, B.B., Sheth, A.L., & Ghodasara, D.J. (2022). Effect of cinnamon (Cinnamomum zeylanicum) Essential Oil as an alternative to Antibiotic Growth Promoter in Broilers. Indian Journal of Veterinary Sciences & Biotechnology, 18(4), 73–80. https://doi.org/10.48165/ijvsbt.18.4.16.
Swain, R.K., Chowdhury, B., & Rao, M.B. (2014). Analgesic Activity of Hydroalcoholic Extract of Cinnamomum zeylanicum Bark in Albino Rats. Journal of Current Pharma Research, 7(1), 2003-2009.
Symeon, G.K., Athanasiou, A., Lykos, N., Charismiadou. M.A., Goliomytis, M., Demiris, N., Ayoutanti, A., Simitzis, P.E., & Deligeorgis, S.G. (2014). The effects of dietary cinnamon (Cinnamomum zeylanicum) oil supplementation on broiler feeding behaviour, growth performance, carcass traits and meat quality characteristics. Annals in Animal Science, 14, 883–895. https://doi.org/10.2478/aoas-2014-0047
Taback, M., Armon, R., & Neeman, I. (1999). Cinnamon extracts inhibitory effect on Helicobacter pylori. Journal of Ethnopharmacology, 67, 269-277.
Tabatabaei, S.M., Badalzadeh, R., Mohammadnezhad, G.R., & Balaei, R. (2015). Effects of Cinnamon extract on biochemical enzymes, TNF-± and NF-ºB gene expression levels in liver of broiler chickens inoculated with Escherichia coli. Pesqui Veterinária Brasilica, 35, 781–787. https://doi.org/10.1590/S0100-736X2015000900003
Thirumalaisamy, R., Jayanthi, B., Rathika, R., & Selvankumar, T. (2008). Spontaneous emulsification techniques of green/food grade nanoemulsions. In Bio-Based Nanoemulsions for Agri-Food Applications (pp. 137-152). Elsevier. https://doi.org/10.1016/ B978-0-323-89846-1.00001-2
Tiihonen, K., Kettunen, H., Bento, M.H., Saarinen, M., Lahtinen, S., Ouwehand, A.C., Schulze, H., & Rautonen, N. (2010). The effect of feeding essential oils on broiler performance and gut microbiota. British Poultry Science Journal, 51, 381–392. https://doi.org/10.1080/00071668.2010.496446
Tiwari, R., Latheef, S.K., Ahmed, I., Iqbal, H.M.N., Bule, M.H., Dhama, K., Samad, H.A., Karthik, K., Alagawany, M., El-Hack, M.E.A., Yatoo, M.I., & Farag, M.R. (2018). Herbal immunomodulators - A remedial panacea for designing and developing effective drugs and medicines: current scenario and future prospects. Current Drug Metabolism, 19(3), 264-301. https://doi.org/10.2174/1389200219666180129125436.
Toghyani, M., Gheisari, A., Ghalamkari, G., & Eghbalsaied, S. (2011). Evaluation of cinnamon and garlic as antibiotic growth promoter substitutions on performance, immune responses, serum biochemical and haematological parameters in broiler chicks. Livestock Science, 138, 167–173. https://doi.org/10.1016/ j.livsci.2010.12.018.
Torki, M. Akbari, M., & Kaviani, K. (2015). Single and combined effects of zinc and cinnamon essential oil in diet on productive performance, egg quality traits, and blood parameters of laying hens reared under cold stress condition. International Journal of Biometeorology, 59, 1169–1177.
Tung, Y.T., Chua, M.T., Wang, S.Y., & Chang, S.T. (2008). Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs. Bioresource Technology, 99(9), 3908-3913. https://doi.org/ 10.1016/j.biortech.2007.07.050
Uddin, T.M., Chakraborty, A.J., Khusro, A., Zidan, B.R.M., Mitra, S., Emran, T.B., Dhama, K., Ripon, M.K.H., Gajdács, M., Sahibzada, M.U.K., Hossain, M.J., & Koirala, N. (2021). Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects. Journal of Infection and Public Health, 14(12), 1750-1766. https://doi.org/10.1016/ j.jiph.2021.10.020
Upadhyaya, I., Upadhyay, A., Kollanoor-Johny, A., Mooyottu, S., Baskaran, S.A., Yin, H.B., Schreiber, D.T., Khan, M.I., Darre, M.J., Curtis, P.A., & Venkitanarayanan, K. (2015). In-feed supplementation of trans-cinnamaldehyde reduces layer-chicken egg-borne transmission of Salmonella enterica serovar enteritidis. Applied and Environmental Microbiology, 81(9), 2985-2994. https://doi.org/10.1128%2FAEM.03809-14
Vangalapati, M., Satya, N.S., Prakash, D.V.S., & Avanigadda, S. (2012). A review on pharmacological activities and clinical effects of cinnamon species. Research Journal of Pharmaceutical Biological & Chemical Sciences, 3: 653-663. https://www.rjpbcs.com/pdf/2012_3(1)/80.pdf
Windisch, W., Schedle, K., Plitzner, C., & Kroismayr, A. (2008). Use of phytogenic products as feed additives for swine and poultry. Animal Science Journal, 86, E140–E148. https://doi.org/10.2527/jas.2007-0459
Yadav, A.S., Kolluri, G., Gopi, M., Karthik, K., Malik, Y.S., & Dhama, K. (2016). Exploring alternatives to antibiotics as health promoting agents in poultry- a review. Journal of Experimental Biology and Agricultural Sciences, 4(3s), 368-383. http://dx.doi.org/10.18006/2016.4(3S).368.383
Yang, C., Diarra, M. S., Choi, J., Rodas-Gonzalez, A., Lepp, D., Liu, S., Lu, P., Mogire, M., Gong, J., Wang, Q., & Yang, C. (2021). Effects of encapsulated cinnamaldehyde on growth performance, intestinal digestive and absorptive functions, meat quality and gut microbiota in broiler chickens. Translational Animal Science, 5(3), txab099. https://doi.org/10.1093/tas/txab099
Yang, C., Kennes, Y. M., Lepp, D., Yin, X., Wang, Q., Yu, H.,
Yang, C., Gong, J., & Diarra, M. S. (2020). Effects of encapsulated cinnamaldehyde and citral on the performance and cecal microbiota of broilers vaccinated or not vaccinated against coccidiosis. Poultry science, 99(2), 936–948. https://doi.org/ 10.1016/j.psj.2019.10.036
Yang, Y.F., Zhao, L.L., Shao, Y.X., Liao, X.D., Zhang, L.Y., Lu, L., & Luo, X.G. (2019). Effects of dietary graded levels of cinnamon essential oil and its combination with bamboo leaf flavonoid on immune function, antioxidative ability and intestinal microbiota of broilers. Journal of Integrated Agriculture, 18, 2123–2132. https://doi.org/10.1016/S2095-3119(19)62566-9
Yin, Y., Lei, F., Zhu, L., Li, S., Wu, Z., Zhang, R., Gao, G.F., Zhu, B., & Wang, X. (2010). Exposure of different bacterial inocula to newborn chicken affects gut microbiota development and ileum gene expression. The ISME Journal, 4, 367–376.
Zaefarian, F., Abdollahi, M. R., Cowieson, A., & Ravindran, V. (2019). Avian Liver: The Forgotten Organ. Animals, 9(2), 63. https://doi.org/10.3390/ani9020063
Zebeaman, M., Tadesse, M. G., Bachheti, R. K., Bachheti, A., Gebeyhu, R., & Chaubey, K. K. (2023). Plants and Plant-Derived Molecules as Natural Immunomodulators. BioMed research international, 2023, 7711297. https://doi.org/10.1155/2023/7711297
Zeng, Z., Zhang, S., Wang, H., & Piao, X. (2015). Essential oil and aromatic plants as feed additives in non-ruminant nutrition: A review. Journal of Animal Science & Biotechnology, 6, 7.
Zhai, H., Liu, H., Wang, S., Wu, J., & Kluenter, A.M. (2018). Potential of essential oils for poultry and pigs. Animal Nutrition, 4, 179–186. https://doi.org/10.1016/j.aninu.2018.01.005
Zhu, C., Yan, H., Zheng, Y., Santos, H.O., Macit, M.S., & Zhao, K. (2020). Impact of cinnamon supplementation on cardiometabolic biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials. Complementary & Therapeutic Medicine, 53, 102517. https://doi.org/10.1016/j.ctim.2020.102517.
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