iNCOVACC COVID-19 vaccine: A Twitter based Social Media Analysis Using Natural Language Processing, Sentiment Analysis, and Topic Modelling
DOI:
https://doi.org/10.18006/2023.11(1).150.157Keywords:
iNCOVACC vaccine, COVID-19, Social media tweets, IndiaAbstract
Most, if not all, the vaccine candidates designed to counteract COVID-19 due to SARS-CoV-2 infection require parenteral administration. Mucosal immunity established by vaccination could significantly contribute to containing the SARS-CoV-2 pandemic, which is spread by infected respiratory secretions. The world has been impacted on many fronts by the COVID-19 pandemic since early 2020 and has yet to recover entirely from the impact of the crisis. In late 2022 and early 2023, China experienced a new surge of COVID-19 outbreaks, mainly in the country's northeastern region. With the threat of new variants like XBB 1.5 and BF.7, India might experience a similar COVID-19 surge as China and needs to be prepared to avoid destruction again. An intranasal vaccine can elicit multiple immunological responses, including IgG neutralization, mucosal IgA production, and T-cell responses. In order to prevent further infection and the spread of COVID-19, local immune responses in the nasal mucosa are required. iNCOVACC is a recombinant vaccine vectored by an adenovirus that contains a SARS-CoV-2 spike protein that has been pre-fusion stabilized. This vaccine candidate has shown promise in both early and late-stage clinical trials. iNCOVACC has been designed for intranasal administration via nasal drops. The nasal delivery system was created to reduce expenses for those living in poor and moderate-income countries. The newly introduced intranasal COVID vaccine will be beneficial in mass immunizing the public as it does not need any syringe and can be proven to be an effective method to boost immunity against the SARS-CoV-2 virus. This study uses natural language processing (NLP) techniques to analyze the Indian citizen's perceptions of the newly developed iNCOVACC vaccine in social media. For this study, we have used social media posts (tweets) as data. We have analyzed 125,300 tweets to study the general perception of Indian citizens regarding the iNCOVACC vaccine. Our results have indicated 43.19% of social media posts discussing the COVID-19 nasal vaccine in a neutral tone, nearly 34.29% of social media posts are positive, and 22.5% of social media posts discussions are negative. The general positive feeling that the iNCOVACC vaccine will work and the risks in the new vaccine are the two significant aspects Indian citizens voice out in social media posts about the iNCOVACC vaccine.
References
Akkız, H. (2022). The Biological Functions and Clinical Significance of SARS-CoV-2 Variants of Corcern. Frontiers in Medicine, 9. doi: 10.3389/fmed.2022.849217. DOI: https://doi.org/10.3389/fmed.2022.849217
Alu, A., Chen, L., Lei, H., Wei, Y., Tian, X., & Wei, X. (2022). Intranasal COVID-19 vaccines: From bench to bed. EBioMedicine, 76, 103841. doi: 10.1016/j.ebiom.2022.103841. DOI: https://doi.org/10.1016/j.ebiom.2022.103841
Chakraborty, S., Mohapatra, R. K., Chandran, D., Alagawany, M., Sv, P., Islam, M. A., Chakraborty, C., & Dhama, K. (2022). Monkeypox vaccines and vaccination strategies: Current knowledge and advances. An update – Correspondence. International Journal of Surgery, 105, 106869.doi: 10.1016/j.ijsu.2022.106869 DOI: https://doi.org/10.1016/j.ijsu.2022.106869
Chavda, V. P., Vora, L. K., Pandya, A. K., & Patravale, V. B. (2021). Intranasal vaccines for SARS-CoV-2: From challenges to potential in COVID-19 management. Drug discovery today, 26(11), 2619–2636. https://doi.org/10.1016/j.drudis.2021.07.021 DOI: https://doi.org/10.1016/j.drudis.2021.07.021
Chen, J., Wang, P., Yuan, L., Zhang, L., et al. (2022). A live attenuated virus-based intranasal COVID-19 vaccine provides rapid, prolonged, and broad protection against SARS-CoV-2. Science Bulletin, 67(13), 1372–1387. doi: 10.1016/j.scib.2022.05.018 DOI: https://doi.org/10.1016/j.scib.2022.05.018
Coccia M. (2022). Optimal levels of vaccination to reduce COVID-19 infected individuals and deaths: A global analysis. Environmental research, 204(Pt C), 112314. https://doi.org/ 10.1016/j.envres.2021.112314 DOI: https://doi.org/10.1016/j.envres.2021.112314
Dhama, K., Chandran, D., Chopra, H., Islam, Md. A., Emran, T. B., et al. (2022a). SARS-CoV-2 emerging Omicron subvariants with a special focus on BF.7 and XBB.1.5 recently posing fears of rising cases amid ongoing COVID-19 pandemic. Journal of Experimental Biology and Agricultural Sciences, 10(6), 1215–1221. doi: 10.18006/2022.10(6).1215.1221 DOI: https://doi.org/10.18006/2022.10(6).1215.1221
Dhama, K., Dhawan, M., Tiwari, R., Emran, T.B., et al. (2022b). COVID-19 intranasal vaccines: current progress, advantages, prospects, and challenges. Human Vaccines & Immunotherapeutics, 18(5), 2045853. doi: 10.1080/21645515.2022.2045853. DOI: https://doi.org/10.1080/21645515.2022.2045853
Dhama, K., Khan, S., Tiwari, R., Sircar, S., Bhat, S., Malik, Y. S., Singh, K. P., Chaicumpa, W., Bonilla-Aldana, D. K., & Rodriguez-Morales, A. J. (2020). Coronavirus Disease 2019-COVID-19. Clinical microbiology reviews, 33(4), e00028-20. https://doi.org/ 10.1128/CMR.00028-20. DOI: https://doi.org/10.1128/CMR.00028-20
Dhama, K., Nainu, F., Frediansyah, A., Yatoo, M. I., et al. (2023). Global emerging Omicron variant of SARS-CoV-2: Impacts, challenges and strategies. Journal of infection and public health, 16(1), 4–14. https://doi.org/10.1016/j.jiph.2022.11.024. DOI: https://doi.org/10.1016/j.jiph.2022.11.024
Gautam, M., Sahai, N., Yadav, A.S., & Tomar, M. (2022). Sentiment analysis about COVID-19 vaccine on Twitter data: Understanding Public opinion. 6thInternational Conference on Intelligent Computing and Control Systems. Advance online publication. Doi: https://doi.org/10.1109/ICICCS53718.2022.9788122. DOI: https://doi.org/10.1109/ICICCS53718.2022.9788122
He, X., Chen, X., Wang, H., Du, G., & Sun, X. (2023). Recent advances in respiratory immunization: A focus on COVID-19 vaccines. Journal of Controlled Release, 355, 655-674. doi: 10.1016/j.jconrel.2023.02.011. DOI: https://doi.org/10.1016/j.jconrel.2023.02.011
Hussain, A., Tahir, A., Hussain, Z., & Sheikh, Z., et al. (2021). Aritifical Intelligence-Enabled Analysis of Public Attitudes on Facebook and Twitter Toward COVID-19 Vaccines in the United Kingdom and the United States: Observational Study. Journal of Medical Internet Research, 23(4):e26627. DOI: https://doi.org/10.2196/26627. DOI: https://doi.org/10.2196/26627
Kelleni M. T. (2023). Evolution of SARS CoV-2 Omicron subvariants BF.7 and XBB.1.5: Time to follow Africa and abort all COVID restrictions. The Journal of infection, S0163-4453(23)00030-0. Advance online publication. https://doi.org/10.1016/j.jinf.2023.01.027. DOI: https://doi.org/10.1016/j.jinf.2023.01.027
Lanyi, K., Green, R., Craig, D., & Marshall, C. (2022). COVID-19 Vaccine Hesistancy: Analysing Twitter to Identify Barriers to Vaccination in a low uptake region of the UK. Frontiers in Digital Health. DOI:https://doi.org/10.3389/fdgth.2021.804855. DOI: https://doi.org/10.3389/fdgth.2021.804855
Ljajic, A., Prodanovic, N., Medvecki, D., & Mitrovic, J., et al. (2022). Uncovering the reasons behind COVID-19 Vaccine hesitancy in Serbia: Sentiment-Based Topic modelling. Journal of Medical Internet Research. DOI: https://doi.org/10.2196/42261. DOI: https://doi.org/10.2196/preprints.42261
Nakahashi-Ouchida, R., Fujihashi, K., Kurashima, Y., Yuki, Y., & Kiyono, H. (2023). Nasal vaccines: solutions for respiratory infectious diseases. Trends in Molecular Medicine, 29(2), 124-140. doi: 10.1016/j.molmed.2022.10.009. DOI: https://doi.org/10.1016/j.molmed.2022.10.009
Prabagar, K., Srikandabala, K., Loganathan, N., Silva, D.D., et.al (2022). Investigating COVID-19 vaccine messaging in Online Social networks using artificial intelligence. 15th International Conference on Human System Interaction (HSI), IEEE Explore. DOI: https://doi.org/10.1109/HSI55341.2022.9869484. DOI: https://doi.org/10.1109/HSI55341.2022.9869484
Praveen, S. V., Ittamalla, R., & Deepak, G. (2021a). Analyzing Indian general public's perspective on anxiety, stress and trauma during Covid-19 - A machine learning study of 840,000 tweets. Diabetes & metabolic syndrome, 15(3), 667–671. https://doi.org/10.1016/j.dsx.2021.03.016 DOI: https://doi.org/10.1016/j.dsx.2021.03.016
Praveen, S. V., Ittamalla, R., & Deepak, G. (2021b). Analyzing the attitude of Indian citizens towards COVID-19 vaccine - A text analytics study. Diabetes & Metabolic Syndrome, 15(2), 595–599. doi: 10.1016/j.dsx.2021.02.031 DOI: https://doi.org/10.1016/j.dsx.2021.02.031
Praveen, S.V., & Ittamalla, R. (2020a). General public's attitude toward governments implementing digital contact tracing to curb COVID-19 - a study based on natural language processing. International Journal of Pervasive Computing and Communications, 18, 485-490. doi: 10.1108/ijpcc-09-2020-0121 DOI: https://doi.org/10.1108/IJPCC-09-2020-0121
Praveen, S.V., & Ittamalla, R. (2020b). Psychological Issues Covid-19 Survivors Face—A Text Analysis Study. Journal of Loss and Trauma, 1–3. doi: 10.1080/15325024.2020.1864127 DOI: https://doi.org/10.1080/15325024.2020.1864127
Praveen, S.V., & Ittamalla, R. (2021a). An analysis of attitude of general public toward COVID-19 crises – sentimental analysis and a topic modeling study. Information Discovery and Delivery. doi: 10.1108/idd-08-2020-0097 DOI: https://doi.org/10.1108/IDD-08-2020-0097
Praveen, S.V., & Ittamalla, R. (2021b). Analyzing Indian citizen's perspective towards government using wearable sensors to tackle COVID-19 crisis—A text analytics study. Health policy and technology, 10, 100521. doi: 10.1016/j.hlpt.2021.100521 DOI: https://doi.org/10.1016/j.hlpt.2021.100521
Praveen, S.V., & Ittamalla, R. (2022). What concerns the general public the most about monkeypox virus? – A text analytics study based on Natural Language Processing (NLP). Travel Medicine and Infectious Disease, 49, 102404. doi: 10.1016/j.tmaid.2022.102404 DOI: https://doi.org/10.1016/j.tmaid.2022.102404
Praveen, S.V., Ittamalla, R., & Subramanian, D. (2020a). Challenges in successful implementation of Digital contact tracing to curb COVID-19 from global citizen's perspective: a text analysis study. International Journal of Pervasive Computing and Communications, 18, 491-498. DOI: https://doi.org/10.1108/IJPCC-09-2020-0147
Praveen, S.V., Ittamalla, R., & Subramanian, D. (2020b). How optimistic do citizens feel about digital contact tracing? - Perspectives from developing countries. International Journal of Pervasive Computing and Communications, 18, 518-526. DOI: https://doi.org/10.1108/IJPCC-10-2020-0166
Praveen, S.V., Lathabhavan, R., & Ittamalla, R. (2021c). What concerns Indian general public on second wave of COVID-19? A report on social media opinions. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 15(3), 829–830. doi: 10.1016/j.dsx.2021.04.001 DOI: https://doi.org/10.1016/j.dsx.2021.04.001
Praveen, S.V., Lorenz, J. M., Ittamalla, R., Dhama, K., Chakraborty, C., Kumar, D. V. S., & Mohan, T. (2022). Twitter-Based Sentiment Analysis and Topic Modeling of Social Media Posts Using Natural Language Processing, to Understand People's Perspectives Regarding COVID-19 Booster Vaccine Shots in India: Crucial to Expanding Vaccination Coverage. Vaccines, 10(11), 1929. doi: 10.3390/vaccines10111929 DOI: https://doi.org/10.3390/vaccines10111929
Praveen, S.V., Tandon, J., Vikas, & Hinduja, H. (2021). Indian citizen's perspective about side effects of COVID-19 vaccine – A machine learning study. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 15(4), 102172. doi: 10.1016/j.dsx.2021.06.009 DOI: https://doi.org/10.1016/j.dsx.2021.06.009
Sah, R., Humayun, M., Baig, E., Farooq, M., et al. (2022). FDA's authorized "JYNNEOS" vaccine for counteracting monkeypox global public health emergency; an update - Correspondence. International journal of surgery (London, England), 107, 106971. https://doi.org/10.1016/j.ijsu.2022.106971. DOI: https://doi.org/10.1016/j.ijsu.2022.106971
Shahnoor, S., Priya, P., & Khatri, G. (2023). Intranasal COVID-19 vaccine: a modern vaccination approach. International Journal of Surgery, 109(1), 43-44. doi: 10.1097/JS9.0000000000000046. DOI: https://doi.org/10.1097/JS9.0000000000000046
Slomski, A. (2022). Intranasal COVID-19 Vaccine Disappointing in First-in-Human Trial. Journal of American Medical Association, 328(20), 2003. doi: 10.1001/jama.2022.18485. DOI: https://doi.org/10.1001/jama.2022.18485
Times, E. (2023, January 26). Bharat Biotech's nasal Covid vaccine iNCOVACC launched. The Economic Times. https://economictimes.indiatimes.com/industry/healthcare/biotech/healthcare/bharat-biotechs-nasal-covid-vaccine-incovacc-launched/articleshow/97345987.cms
Villavicenio, C., Macrohon, J.J., Inbaraj, A., Jeng, H.J., et al. (2021). Twitter Sentiment analysis towards COVID-19 vaccines in the Philippines using Naïve Bayes. Information. DOI: https://doi.org/10.3390/info12050204. DOI: https://doi.org/10.3390/info12050204
Zhou, H., Møhlenberg, M., Thakor, J. C., Tuli, H. S., Wang, P., Assaraf, Y. G., Dhama, K., & Jiang, S. (2022). Sensitivity to Vaccines, Therapeutic Antibodies, and Viral Entry Inhibitors and Advances To Counter the SARS-CoV-2 Omicron Variant. Clinical microbiology reviews, 35(3), e0001422. https://doi.org/10.1128/ cmr.00014-22. DOI: https://doi.org/10.1128/cmr.00014-22
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