Volume 7, Issue 6, December Issue - 2019, Pages:521-528
|Authors: Bassam Oudh Al johny|
|Abstract: Post-translational changes including acetylation are universal phenomena in protein and occur in both prokaryotes and eukaryotes. The process of post-translation modifications is initiated by phosphorylation of the acetyl group through an enzymatic pathway using the acetyltransferase enzyme. It is believed that several processes such as cellular process, DNA replication, bacterial chemotaxis and metabolism depend on protein acetylation. It is worth to say that protein acetylation is extremely important in bacterial virulence, as diverse factors have been involved in bacterial virulence. Therefore, current review article summarizes the role of protein acetylation, its mechanism, techniques of acetylome study and its regulation, which may help in the in-depth understanding of bacterial virulence.|
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