Volume 6, Issue 5, October Issue - 2018, Pages:879-883
|Authors: S.Sivajothi, B.Sudhakara Reddy, Y.V.Prithvidhar Reddy, S.Vani, Kotagiri Ravikanth, Bhaskar Ganguly|
|Abstract: The present study was conducted to determine the alterations in haematological parameters and stress markers in naturally Balantidium coli infected buffaloes, along with this efficacy of polyherbal anti-stressor product Restobal (Restobal®, M/s Ayurvet Limited) was also evaluated against the stress induced by B. coli. In present study, a total of ten apparently healthy buffaloes were selected and considered as control group while twenty buffaloes with natural B. coli infection were included in the disease group and considered for treatment trial. In all the clinical cases, clinical examination and detailed appraisal of haemato-biochemical profiles were carried out. For treatment trial, a total of twenty diseased buffaloes were divided into two groups with ten buffaloes in each group. In therapeutic trials (group I) buffaloes were administered with specific medication against B. coli infection and in herbal trail buffaloes (group II) were administered with specific medication against B. coli infection along with the commercial polyherbal anti stressor product (Restobal). Findings of present study revealed that buffaloes with B. coli infection have reduced haemoglobin levels, total erythrocyte count and monocyte count with increased total leukocyte, neutrophil, lymphocyte, eosinophil count and serum cortisol levels than the apparently healthy buffaloes which indicative of stress due to disease. Buffaloes administered with oral polyherbal anti stressors product showed the significant difference from the group I by elevation of haemoglobin parameters, packed cell volume and serum cortisol levels along with variations in the vital parameters. In conclusion, polyherbal anti stressor product which contains Ocimum sanctum, Phyllanthus emblica, Mangifera indica and Withania somnifera can be recommended along with the specific disease therapeutic protocol in buffaloes to the management of disease induced stress.|
Ahmad MF, Rasad R (2011) Balantidium coli. Medical Parasitology 4th Ed. Jakarta: Faculty of Medicine, University of Indonesia.
Feldman BF, Zinkl JG, Jain NC (2000) Schalms Veterinary Haematology. 5th Edition, Williams and Wilkins, Philadelphia: 21-100.
Kumar A, Singh A, Dora J (2012) Essential perspectives for Emblica officinalis. International Journal of Pharmaceutical and Chemical Sciences 1:11-18.
Padgett DA, Glaser R (2003) How stress influences the immune response. Trends in Immunology 24: 444-448.
Kumar CP, Rawath SS, Kumar YD, Neelima KSSN (2013) Effect of Emblica Officinalis on stress induced biochemical and psychological changes in mice. Global Journal of Medical Research Veterinary Science and Veterinary Medicine 13: 25-28.
Prakash D, Upadhyay G, Gupta C, Pushpangadan P, Singh KK (2012) Antioxidant and free radical scavenging activities of some promising wild edible fruits. International Food Research Journal 19:1109-16.
Reddy BS, Sivajothi S, Rayulu VC (2015) Clinical coccidiosis in adult cattle. Journal of Parasitic Diseases 39: 557-559.
Roy BC, Mondal MMH, Talukder MH, Majumder S (2011)
Prevalence of Balantidium coli in buffaloes at different areas of Mymensingh. Journal of Bangladesh Agricultural University 9 : 67-72.
Schuster FL, Ramirez AL (2008) Current world status of Balantidium coli. Clinical Microbiological Review 21: 626-38.
Sharma V, Agrawal RC, Pandey S (2013) Phytochemical screening and determination of anti-bacterial and antioxidant potential of Glycyrrhiza glabra root extracts. Journal of Environment Research and Development 7 :1552-1558.
Sivajothi S, Reddy BS (2017) Antioxidant status and electrocardiographic changes in buffaloes with Trypanosoma evansi infection. Chemical Science Review and Letters 6: 2573-2576.
Sivajothi S, Reddy BS (2018) Acute fulminating form of Balantidium coli infection in buffaloes. Research & Reviews: Research Journal of Biology 6: 17-19.
Sivajothi S, Reddy YVP, Reddy BS, Vani S, Chandel S, Ravikanth K, Ganguly B (2018a) Evaluation of herbal anti-stressor product (Restobal) during the vaccination stress in buffaloes. International Journal of Current Microbiology and Applied Sciences 7 : 723-727.
Sivajothi S, Reddy BS, Reddy YVP, Vani S, Chandel S, Ravikanth K, Ganguly B (2018b) Assessment of summer stress and management with poly herbal anti-stressor product (restobal) in buffaloes. Journal of Animal Research 8 : 713-717.
Sudan V, Sharma RL, Patya A, Singh PK (2012) An occurrence of clinical balantidiasis in a cross bred cow and its therapeutic management. Journal of Veterinary Parasitology 26: 164-66.
Tarrar MA, Khan MS, Pervez K, Ashraf K, Khan JA, Rehman ZU (2008) Detection and chemotherapy of Balantidium coli in buffaloes around Lahore, Pakistan. Pakistan Journal of Agricultural Sciences 45: 163-166.
Yang EV, Glaser R (2000) Stress-induced immunomodulation: impact on immune defenses against infectious disease. Biomedicine & Pharmacotherapy 54: 245-250.