News Scroll
Most Download Articles
Most Views Articles
E-mail Alerts
Subscribe for TOC Alerts
Search Articles
Creative Commons License
Abstract
Volume 6, Issue 6, December Issue - 2018, Pages:997-1003 |
| Authors: Nouran Y. Hamed, AhmedKandeil, Jamal S. M. Sabir, Salah E. M. Abo-Aba, Nahid H. hajrah, Mohammad K. Al-ghamdi, Alawiah M. Alhibshi, Abdelfatteh El Omri, Areej K. Al-gamdi, Mohamed A. Ali |
| Abstract: Many avian influenza vaccines are currently used to treat avian influenza virus’s infection in many countries of Middle East. Information about the role of antigen content in vaccine efficiency is vital for the choice of ideal vaccines and vaccination programs, in addition to licensing of new avian influenza (AI) vaccines. In present work, we studied the serological response of SPF chicken towards 7 different concentrations of avian influenza H5N1 virus (8HA, 16HA, 32HA, 64HA, 128HA, 256HA, 512 HA). Different concentrations of the vaccine strain of H5N1 virus were prepared and mixed with an adjuvant to prepare experimental vaccines with different concentrations of antigen content. Serological responses of post vaccinated chickens were monitored over the course of 6 weeks. After calculation of hemagglutination inhibition (HI) values for each group to determine the antibody titers, it was found that the maximum antibody levels were produced by antigen contents 512 and 256 HAU. Results of the present study indicated that low antigenic groups have promising protective effect. |
| [Download PDF] |
Editorial Board
Indexed & Listed In
Scopus Cite Score
Scimago Journal Rank
Track manuscript
Manuscript Statistics
Articles Statistics
Publication Statistics