Volume 4 Issue 4 Article 8

Histopathological study of toxicity mixture of cashew apple juice (Anacardium occidentale), cow milk and yogurt on the wistar rat

BOKOSSA YAOU Innocent1, AGBODJOGBE Daniel2, DJOGBE Anayce A. Mikponsé1,*, LOKO Frédéric2, DARBOUX Raphaël3, LOZES Evelyne2, TCHEKESSI C. K. Célestin1 et Pivot SACHI1, BLEOUSSI Roseline1 and MENSAH Guy Apollinaire4

1Laboratory of Microbiology and Food Technologies, University of Abomey-Calavi, 01 BP 526 Cotonou Postal sorting
2Biomedical Analysis Laboratory of the Polytechnic School of Abomey-Calavi, BP 2009 Cotonou
3Histology Laboratory of the Faculty of Health Sciences of the University of Abomey-Calavi, ISBA, Cotonou
4National Institute of agricultural research of Benin 01 BP 884 Recette Principale, Cotonou 01(Benin)

Keywords: Dairy products, Cashew apple juice, Toxicity, Histopathology and Wistar rats

Page No: 435 - 439

Received - April 19, 2016; Revision - May 04, 2016; Accepted - June 28, 2016
Available Online - June 30, 2016

How to Cite


The purpose of this study was to confirm or to deny the general opinion Benin people that the simultaneous consumption of dairy products, cow milk, yogurt (fermented cow's milk) with cashew apple juice is toxic to human and the animal. Histopathological examinations were performed on thirty Wistar rats consist of ten batches. Each batch is consisted of three rats. The first batch has served as a control and the remaining nine were treated differently. Cow milk, yogurt and cashew apple juice either alone or mixed with each others were administered to each rat at the rate of 2.0 ml / 200g of body weight. Histological observation of removed organs (stomach, liver and kidneys) within the treated batch showed that the organs of rats treated with cashew apple juice / cow milk /yogurt (respectively batch 2, 3, and 4) was not showing any structural abnormality. Similar types of findings were reported for the rat group treated with a mixture of juice and milk. However, it was reported that the juice-yogurt association has some action on the liver but it did affect the functioning or anatomy of other analyzed organs. It can be conclude that the juice and cow milk mixture are not toxic to animal cells, but the juice-yogurt mixture has some toxic effect on the liver cells only.

Focus and Scope

JEBAS is an open access journal that provides a suitable platform to researcher for rapid publication of articles in all aspects of biology including microbiology, parasitology, biochemistry, molecular biology, physiology, pathology, health sciences, pharmacology, toxicology, biotechnology, environmental biology, food science, nutrition, agricultural sciences, botany, ethnobotany, forestry, agroforestry, bioinformatics...


Copyright Policy

The entire article published by Journal of Experimental Biology and Agricultural Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License which permits commercial and non-commercial re-use of an open access article, as long as the original author and source are properly attributed...